Quality Inspection for Vials During the Filling and Sealing Process. The VINSPEC HEALTHCARE inspection system covers all inspection requirements that apply to the filling and sealing of vials—inline, at filling speed. As a result, you can quickly detect unwanted process changes, correct the relevant parameter, and ensure high quality output
Feb 1, 2016 · The most commonly used primary packaging for parenteral drug products to date is the rubber stopper and glass vial, sealed with an aluminum crimp cap. The design and choice of primary packaging components, and their combination, requires careful assessment.
With full control over geometry and surface chemistry, our vials can be tailored to meet the different needs of biopharmaceutical customers. Our portfolio also includes special vial containment solutions as microvials for respiratory and sublingual applications, and low delamination propensity vials (LDP) for aggressive compounds.
MilliporeSigma. Crimp top vials, which require an 11mm seal, are available in a variety of styles. These vials have a solid glass finish and are available with a 4.6 or 6.0mm ID opening. The larger opening increases the target area for needle penetration. The crimp seals for these vials are available in a variety. Compare this item.
Autosampling chromatography vials feature high-quality materials to help meet demanding industry specifications and tolerances. Choose from clear borosilicate glass vials and amber vials that can accommodate light-sensitive applications. Boost your supply of laboratory vials at Grainger today!
The vials are Specification Certified to ensure autosampler compatible physical dimensions, and meet all requirements of US, EU, and JPN Pharmacopia. Seal these crimp vials with 20 mm aluminum crimp caps and septa using a manual or electronic crimper tool.
Crimp Top Vial. 12 x 32 mm, ND11. Converted from Type I borosilicate glass tubing. Crimp top vials provide an excellent seal for long term sample storage and analyses involving high volatile solvents. 40% larger opening improves sample accessibility and reduces the risk of autosampler needle damage. Packed in re-closable, tamper-proof evident
Clear 20 ml headspace vials designed to fit most headspace autosamplers.Vials are available in all capacities, materials like plastic vials or glass vials, and in a variety of colors to meet any collection, storage, or analysis need. Tailor vessels for specific media with various translucent manufacturing and different sterility options for precise test results. Choose from the extensive
Use Thermo Scientific 20 mm crimp caps and septa to seal this vial Use Thermo Scientific manual or electronic crimpers and decrimpers to seal and remove your crimp top from the vial Round base vials are compatible with most autosamplers and more easily handled by robotic arms that lift the vial from the tray Buy in bulk for greater savings
Dec 1, 2017 · Disc-style crimping offers a more consistent, commonly used method. In this method, a pressure block applies an appropriate and uniform pressure onto the vial, stopper and seal. A disc then gently and consistently tucks the aluminum under the flange of the vial crown, securing the seal.
Thermo Scientific™ headspace vials are available in clear or amber glass with a round or flat base, a crimp seal with a beveled or square edge finish, or with a screw-thread finish. Headspace vials, septum, and caps can be purchased in various quantities separately or together as convenience kits to fit your laboratory needs. Product Overview
Feb 1, 2016 · The process of the vial closing is a complex interplay of the vial, rubber stopper and crimp cap but also the capping equipment, including the choice of processing parameters and ranges. In this review we describe the challenges regarding CCI and manufacturing defects, such as cosmetic issues associated with the capping process.
Oct 1, 2020 · Reconfiguring Fill/Finish Inspection to Meet COVID-19 Vaccine Goals. Fill/finish inspection for vaccine vials and syringes must remain GMP-compliant while aiming for fast, efficient methods. The global race to produce COVID-19 vaccines under the Operation Warp Speed initiative adds pressure to vaccine manufacturers to have product ready while
Jul 13, 2020 · Consistent Crimp, Consistent CCI. Container closure integrity (CCI) is a critical factor every drug manufacturer and compounder is required to achieve. To achieve CCI, one must consider factors such as vial material, blowback, and stopper design. One vital factor – too often an afterthought – is the aluminum seal. Example of a good crimp
The fill-finish industry is expanding quickly and aseptic processing will continue to require coordination, risk management, and regulatory compliance. Meeting this growing demand for fill-finish services requires: specialized expertise; appropriate equipment; innovations in both emerging technology and business models
