Thermo Scientific™ Nalgene™ PETG Serum Vials with Crimp Finish: Nonsterile, Shrink-Wrapped Modules Protect against leakage, breakage, and contamination. Nalgene PETG Crimp Finish Serum Vials are lighter in weight than glass, and are made for use with stoppers and caps. 7 DWK Life Sciences WHEATON™ CompletePAK™ Clear Kits
A vial (also known as a phial or flacon) is a small glass or plastic vessel or bottle, often used to store medication as liquids, powders or capsules. They can also be used as scientific sample vessels; for instance, in autosampler devices in analytical chromatography.
Aijiren's 2 mL crimp vials and 11 mm crimp vial caps are the perfect fit for HPLC and GC autosamplers across a wide variety of applications, including pharmaceutical, environmental, energy and fuels, forensics, materials science, biopharmaceutical, proteomics, and metabolomics.
20 mL Crimp Top Vial with Write-on Patch and Fill Lines (1000/pack). Our vials are manufactured to specific tolerances that are guaranteed to fit and perform with non-PerkinElmer instruments also. 20 mL Clear Glass Crimp Top Vial with Write-On Patch, 100/pk | PerkinElmer
2 days ago · For glass vials, closure options are either screw vials (closed with a screw cap or dropper) lip vials (closed with a plastic stopper or cork) or crimp vials (closed with a rubber stopper and a metal cap). Plastic vials, which can be molded in plastic, can have other closure systems, such as 'hinge caps' which snap shut when pressed.
non-latex rubber from vial stopper, and fiber-like material from the manufacturing process and could potentially cause serious adverse events in patients. This problem effects all lots Cerezyme, Fabrazyme, Myozyme, Aldurazyme, and Thyrogen.
The most commonly used CCS configuration for parenteral drug products is the glass vial, sealed with a rubber stopper and an aluminum crimp cap. In combination with an adequately designed and controlled aseptic fill/finish processes, a well-designed and characterized capping process is indispensable to ensure product quality and integrity and to minimize rejections during the manufacturing process.
Pharmaceutical Crimping Techniques: How to Improve the Quality of Aluminum Seals. The process of crimping an aluminum seal onto a pre-stoppered vial should not be overlooked or underemphasized. Within the pharmaceutical industry, there is a need for an elegant and effective seal not only from the cosmetic perspective, but also more importantly, because of the correlation between seal quality and container closure integrity.
Abstract. The majority of parenteral drug products are manufactured in glass vials with an elastomeric rubber stopper and a crimp cap. The vial sealing process is a critical process step during fill&finish operations, as it defines the seal quality of the final product. Different critical capping process parameters can impact rubber stopper defects, rubber stopper compression, CCI but also crimp cap quality.
With glass-like transparency, superior break resistance and low risk of chemical interactions, Crystal Zenith vials help to overcome drug-related challenges, including delamination and particulates, and provide an integrated lifecycle solution designed to maintain drug safety, purity and efficacy. Buy Now Request More Information Product Attributes
Jul 13, 2020 · July 13, 2020 Consistent Crimp, Consistent CCI Container closure integrity (CCI) is a critical factor every drug manufacturer and compounder is required to achieve. To achieve CCI, one must consider factors such as vial material, blowback, and stopper design. One vital factor – too often an afterthought – is the aluminum seal.
A correctly crimped vial is neither over-crimped nor under-crimped. Over-crimping may cause coring or poor septum resealing. Under-crimping can cause evaporation problems. With proper adjustment of the vial crimpers, perfect crimping can be achieved every time. When the vial is crimped perfectly, the cap should not be able to rotate and the
The vial sealing process is a critical process step during fill-and-finish operations, as it defines the seal quality of the final product. Different critical capping process parameters can affect rubber stopper defects, rubber stopper compression, container closure integrity, and also crimp cap quality.
Aug 4, 2021 · Vial crimper and Decapper are vials that people use in a laboratory setting. They are designed to be used with vials for blood or other types of samples, and there is usually a special type of needle on the crimper tool to draw out liquid from vials. Vial crimper has two different parts: The top part has an opening that can stretch open so it
LAY ABSTRACT: Pharmaceutical vials are typically closed off with an elastomeric stopper that is secured onto the vial with an aluminum crimp cap (or seal) such that the entire assembly is meant to protect the vial's contents from external contamination. Therefore, the capping process is critical for ensuring container closure integrity.
