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The Australian Customer’s V947 Autosampler Vial Order is Completed
The Australian Customer’s V947 Autosampler Vial Order is Completed
American Customer Ordered 100,000 Boxes of 9-425 2ml HPLC Vials
American Customer Ordered 100,000 Boxes of 9-425 2ml HPLC Vials
5000-boxes-of-blue-screw-cap-10-425-hplc-vial-sent-to-singapore
5000-boxes-of-blue-screw-cap-10-425-hplc-vial-sent-to-singapore
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Set the AQL by defect class, not by product family
Set the AQL by defect class, not by product family
April 5, 2018
Set the AQL by defect class, not by product family
A 50,000-vial lot of 9 mm screw-thread vials left the line at 12.4 mm body OD with a mean septum puncture force of 4.1 N, and the outgoing inspection record still cleared it. Four weeks later a customer running a 96-well autosampler flagged 11 coring events in 2,000 injections. The measurement that explained the complaint was not the mean puncture force. It was the lower 3-sigma limit on the 30-vial pull sample, which sat at 2.6 N, below the 3.0 N floor the customer’s needle geometry ...
The traceability chain for a consumable has five links, and most labs can
The traceability chain for a consumable has five links, and most labs can
April 5, 2018
The traceability chain for a consumable has five links, and most labs can
The auditor picked four vials at random from an opened box of 100 and asked for the calibration certificate behind the glass. The lab had the supplier’s ISO 9001 certificate, a certificate of analysis with a lot number, and a purchasing record. What it could not produce was a document tying the dimensional tolerance on that lot to a measurement traceable to a national standard. That gap cost the lab a finding under ISO/IEC 17025:2017 clause 6.5, and it is the single most common tracea...
Ghost peaks from vials are almost always extractables, not carryover
Ghost peaks from vials are almost always extractables, not carryover
April 5, 2018
Ghost peaks from vials are almost always extractables, not carryover
A 12 x 32 mm clear vial with a silicone/PTFE septum sat in a 40 °C autosampler tray for 11 hours and put a 0.8 mAU peak at 8.3 minutes into a gradient blank that had been flat at t=0. The method’s LOQ was 0.05 mAU. Nothing on the instrument had changed. The vial had been in the tray since the previous afternoon. That is the shape most HPLC vial ghost peaks take: they arrive late, they scale with residence time and temperature, and they disappear the moment you change to a different lo...