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The Australian Customer’s V947 Autosampler Vial Order is Completed
The Australian Customer’s V947 Autosampler Vial Order is Completed
American Customer Ordered 100,000 Boxes of 9-425 2ml HPLC Vials
American Customer Ordered 100,000 Boxes of 9-425 2ml HPLC Vials
5000-boxes-of-blue-screw-cap-10-425-hplc-vial-sent-to-singapore
5000-boxes-of-blue-screw-cap-10-425-hplc-vial-sent-to-singapore
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Tray height tolerance is the variable nobody measures until a run dies
Tray height tolerance is the variable nobody measures until a run dies
April 5, 2018
Tray height tolerance is the variable nobody measures until a run dies
A 12 x 32 mm vial sitting 1.8 mm high in a tray well will pick up cleanly on Monday and fail with a “no sample” error on Thursday after the same tray has been loaded and unloaded eleven times. I have watched that exact drift take down a 96-position run at 3 a.m., and the vial was never the problem. The autosampler pickup error and misalignment that labs blame on “bad vials” is almost always a geometry stack: tray height, gripper tolerance, cap seating, and the small ...
Which quality-system items actually predict vial failures
Which quality-system items actually predict vial failures
April 5, 2018
Which quality-system items actually predict vial failures
A 6,000-piece lot of 9 mm screw-thread vials failed incoming dimensional check at 12.31 mm outside diameter against a 12.00 ± 0.20 mm print, and the autosampler on the line had been throwing “vial not found” errors on roughly 1 in 400 positions for three weeks. The certificate of analysis said “conforms.” That gap, between a supplier’s stated conformance and the measurement you can actually reproduce, is what an HPLC vial supplier audit checklist exists to clos...
Set the AQL by defect class, not by product family
Set the AQL by defect class, not by product family
April 5, 2018
Set the AQL by defect class, not by product family
A 50,000-vial lot of 9 mm screw-thread vials left the line at 12.4 mm body OD with a mean septum puncture force of 4.1 N, and the outgoing inspection record still cleared it. Four weeks later a customer running a 96-well autosampler flagged 11 coring events in 2,000 injections. The measurement that explained the complaint was not the mean puncture force. It was the lower 3-sigma limit on the 30-vial pull sample, which sat at 2.6 N, below the 3.0 N floor the customer’s needle geometry ...