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The Australian Customer’s V947 Autosampler Vial Order is Completed
The Australian Customer’s V947 Autosampler Vial Order is Completed
American Customer Ordered 100,000 Boxes of 9-425 2ml HPLC Vials
American Customer Ordered 100,000 Boxes of 9-425 2ml HPLC Vials
5000-boxes-of-blue-screw-cap-10-425-hplc-vial-sent-to-singapore
5000-boxes-of-blue-screw-cap-10-425-hplc-vial-sent-to-singapore
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What actually varies between vial lots
What actually varies between vial lots
April 5, 2018
What actually varies between vial lots
I have watched a validated method fail on a Monday morning because someone opened a new case of vials from a different lot. The chromatograms were not catastrophically wrong. They were just slightly worse: peak area RSD crept from 0.4% to 1.8%, one late-eluting peak grew a shoulder, and the autosampler started logging a few “no sample” errors on the first injection of each tray. Nothing in the method had changed. The vials had. Finding that took three days of instrument checks t...
Sizing an HPLC vial to real sample volume and injection count
Sizing an HPLC vial to real sample volume and injection count
April 5, 2018
Sizing an HPLC vial to real sample volume and injection count
I spent the better part of a decade watching analysts pick a vial by grabbing whatever case was closest to the balance, and then I spent another decade fielding the phone calls when those vials ran dry at 3 a.m. mid-sequence. Sizing a vial to your sample volume and injection count is not a glamorous calculation, but it is one of the few places in an analytical method where a two-minute arithmetic check saves you a re-run, a lost plate, and a conversation with a client about why their 96 sam...
What coring actually is, mechanically
What coring actually is, mechanically
April 5, 2018
What coring actually is, mechanically
I still remember the Monday morning when a routine batch of 96 samples came back with a needle pressure error on the third injection. The autosampler had been running the same method for six months. Nothing changed on the LC side. What changed was the vial lot. We had switched to a lower-cost 9 mm screw-thread vial with a thin silicone septum, and by the time we pulled the needle, the tip was curled like a fishhook and the septum had a clean 0.8 mm plug punched straight through it. That plu...