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The Australian Customer’s V947 Autosampler Vial Order is Completed
The Australian Customer’s V947 Autosampler Vial Order is Completed
American Customer Ordered 100,000 Boxes of 9-425 2ml HPLC Vials
American Customer Ordered 100,000 Boxes of 9-425 2ml HPLC Vials
5000-boxes-of-blue-screw-cap-10-425-hplc-vial-sent-to-singapore
5000-boxes-of-blue-screw-cap-10-425-hplc-vial-sent-to-singapore
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Ghost peaks from vials are almost always extractables, not carryover
Ghost peaks from vials are almost always extractables, not carryover
April 5, 2018
Ghost peaks from vials are almost always extractables, not carryover
A 12 x 32 mm clear vial with a silicone/PTFE septum sat in a 40 °C autosampler tray for 11 hours and put a 0.8 mAU peak at 8.3 minutes into a gradient blank that had been flat at t=0. The method’s LOQ was 0.05 mAU. Nothing on the instrument had changed. The vial had been in the tray since the previous afternoon. That is the shape most HPLC vial ghost peaks take: they arrive late, they scale with residence time and temperature, and they disappear the moment you change to a different lo...
Why the septum polymer, not the glass, is the decision you usually get wrong
Why the septum polymer, not the glass, is the decision you usually get wrong
April 5, 2018
Why the septum polymer, not the glass, is the decision you usually get wrong
A 12 x 32 mm screw vial capped with a red PTFE/silicone septum and run on a 40 °C autosampler tray with 100% acetonitrile will lose its seal integrity faster than most labs expect. I watched a stability batch fail at day four because the silicone layer had absorbed enough acetonitrile to swell 14% by volume, and the resulting compression set let the septum lift under the needle. The injection volume drifted from 5.0 µL to 4.3 µL across the run. That is the kind of failure you only prevent b...
Start with consumption in vials per working day, not vials per month
Start with consumption in vials per working day, not vials per month
April 5, 2018
Start with consumption in vials per working day, not vials per month
A buyer I work with runs 340 injections a day across two Aijiren autosamplers, and last March her line went down for nine days because a 9 mm screw-thread vial order sat on a water in Guangzhou. The reorder point on her spreadsheet was 4,000 vials. She had 4,200 on hand the morning the stockout started. That number was built on a 21-day average lead time, and the actual shipment took 34 days. The gap between a reorder point and a stockout is not the average lead time. It is the lead-ti...